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Anaplastic Lymphoma Kinase (ALK) is a relatively new as an oncogenic driver and a therapeutic target in Non-Small Cell Lung Cancer (NSCLC); the prognostic. Abstract: Patients with non-small cell lung cancer (NSCLC) who harbor anaplastic lymphoma kinase (ALK) gene rearrangements can derive significant clinical. The ALK Break-Apart FISH Probe Kit detects rearrangement of the anaplastic lymphoma kinase (ALK) gene in NSCLC. Up to 5% of non-squamous NSCLC carry ALK.

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Screening test for all ALK fusions. Use if the companion diagnostic test for crizotinib is required. Does not identify the translocation partner or variant. ALK gene rearrangement (2p23) by FISH: Message Please provide most recent Pathology report. Test Code MDFCPCGR2PF or Alias/See Also ALK. genetic diagnosis, ALK rearrangement gene, Non-small cell Lung cancer, It is possible to detect close to 80% of the ALKrearrangement genes using.

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In lung cancer, ALK rearrangement correlates with EML4-ALK gene fusion, and it has been observed in approximately 5% of lung cancers, predominantly. ALK gene rearrangement (2p23) by FISH: Message Please provide most recent Pathology report. Test Code MDFCPCGR2PF or Alias/See Also ALK. Request PDF | ALK gene rearrangement status in non-squamous non-small cell lung carcinoma in the Middle Eastern population | Background: Worldwide.